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Editorial Reviews

Big Blue Ball is the long-awaited, much-anticipated collection of stand-out tracks culled from the all-star, pan-global collaborations that took place over three years of Peter Gabriel s legendary Recording Week gatherings at his state-of-the-art Real World Studios in the English countryside.

Produced by Peter Gabriel, Karl Wallinger (of World Party, Waterboys) and Stephen Hague (Pet Shop Boys, OMD), it s a nonstop stream of poignant, sterling performances by a truly stellar lineup of artists-- including Gabriel, Wallinger, Sinead O Connor, Natacha Atlas, Iarla O Lionaird and James McNally (both of Afro Celt Sound System), Papa Wemba, Joseph Arthur, Tanzania s late music legend Hukwe Zawose, Hungary s Marta Sebestyen, Tim Finn, Cameroonian starFrancis Bebey, Vernon Reid, Justin Adams, Jah Wobble, Billy Cobham, Rupert Hine, gospel group the Holmes Brothers, flamenco guitarist Juan Canizares, Japanese percussionist Joji Hirota, and many more...in all totaling 75 artists from over 20 countries.

It s like a wall of sound coming at you, listening to the planet from outer space, says Karl Wallinger of the final mix. It s a real world-view of music, a snapshot of the music-making continents at that time. It s a more apt time to release it now than ever before. I think it s actually gathered weight with time, because it s people from all over the world playing together, just getting on together. There s an iconic aspect about that which is probably more important now. Things have become more partisan. It s a timely reminder of how you can cooperate.

Big Blue Ball s songs were created and recorded between 1991 and 1995, but the album has been an active work-in-progress at Real World ever since, a labor of love with ace producer Stephen Hague working closely with Peter Gabriel and Karl Wallinger. Holding the disparate elements in place is the powerful backbone of big drum tracks underpinning many of the songs. Wallinger says, Everyone was in orbit around this groove, and there is a universal language of dance, of dance grooves. That groove is the one bit that s non-denominational on the album.

Says Peter Gabriel, It s a fine wine ready to be drunk. It was the most fun music making I ve ever had. I d love to do it again.

Big Blue Ball

CURRENT ISSUE
September, 2021

No. 106 (9)

2020 Impact Factor: 9.941 Submission > Acceptance: 52 days
ARTICLES IN THREE SENTENCES
Article

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma

This open-label, single-arm study investigated the long-term efficacy of tafasitamab plus lenalidomide in 81 patients with relapsed/refractory diffuse large B-cell lymphoma. The response rate was 57.5%, including complete responses in 40.0% of patients, and the median duration of response was 43.9 months. This treatment is a valuable option for patients not eligible for autologous stem-cell transplantation.

Johannes Duell et al.

Case Report

Clinical genomic profiling of novel grey zone lymphoma paired lesions with sequential central nervous system involvement in two adolescent patients

Grey zone lymphoma is a B-cell lymphoma, unclassifiable, with features intermediate between those of large B-cell lymphoma and classic Hodgkin lymphoma. The in-depth study of the two adolescent patients described in this case report expands the clinicopathological and genomic spectrum of this rare pediatric disease. Moreover, it provides information on their response to treatment.

Cagla Y. Benkli et al.

Article

CAMT-MPL: congenital amegakaryocytic thrombocytopenia caused by MPL mutations - heterogeneity of a monogenic disorder - a comprehensive analysis of 56 patients

The clinical picture of 56 patients with congenital amegakaryocytic thrombocytopenia due to MPL mutations was much more varied than previously thought. Twenty-five per cent of them had no signs of thrombocytopenia at birth, and 50% had non-hematologic defects. Pancytopenia developed in (nearly) all patients and hematopoietic stem-cell transplantation was effective in 87% of cases.

Manuela Germeshausen et al.

Article

Oxidative stress activates red cell adhesion to laminin in sickle cell disease

Sickle red blood cells exhibit abnormal adhesion to laminin mediated by Lu/BCAM protein at their surface. This study provides evidence of the involvement of oxidative stress in post-translational modifications of Lu/BCAM which impact the protein’s distribution and cis-interaction with glycophorin C at the cell surface activating its adhesive function in dense sickle red cells. The authors speculate that antioxidant drugs might attenuate this phenomenon.

Maria Alejandra Lizarralde-Iragorri et al.

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